最近国语视频免费观看在线播放_俺来啦俺去啦_色妞www精品一级视频_欧美一级黄色片在线观看

最近搜索：細胞培養 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>活性依賴的神經保護肽抗體
活性依賴的神經保護肽抗體
  • 產品貨號：
    BN40204R
  • 中文名稱：
    活性依賴的神經保護肽抗體
  • 英文名稱：
    Rabbit anti-ADNP Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規格

    售價

    備注

  • BN40204R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Cow) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40204R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Cow) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱ADNP
中文名稱活性依賴的神經保護肽抗體
別    名Activity dependent neuroprotective protein; Activity dependent neuroprotector; NAP; KIAA0784


研究領域細胞生物  神經生物學  細胞凋亡  轉錄調節因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Cow, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量114kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ADNP:331-400/1102 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.

Function:
Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.

Subcellular Location:
Nucleus (Potential).

Tissue Specificity:
Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.

Similarity:
Contains 9 C2H2-type zinc fingers.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q9H2P0

Gene ID:
23394

Database links:

Entrez Gene: 23394 Human

Omim: 611386 Human

SwissProt: Q9H2P0 Human

Unigene: 570355 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

是一個潛在的轉錄調節因子，參與正常細胞與腫瘤細胞的增殖調控。
廣泛分布于大腦、小腦等組織，在肺、腎、小腸以及睪丸等組織也有微弱的表達。對體外培養的glia缺失神經元細胞有保護作用.